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Physical causes of mental disorders have been sought in history.Hippocrates was important in this tradition as he identified syphilis as a disease and was therefore an early proponent of the idea that psychological disorders are biologically caused.Now often seen as the very epitome of rational thought and as the founder of philosophy, Socrates freely admitted to experiencing what are now called "command hallucinations" (then called his 'daemon'). The humoral theory fell out of favor in some quarters. 124–40 BC), who practiced in Rome, discarded it and advocated humane treatments, and had insane persons freed from confinement and treated them with natural therapy, such as diet and massages. AD 30–90) argued that it is hard to pinpoint from where a mental illness comes. 200), practicing in Greece and Rome, revived humoral theory.Playwrights such as Homer, Sophocles and Euripides described madmen driven insane by the gods, imbalanced humors or circumstances.

However, Socrates considered positive aspects including prophesying (a 'manic art'); mystical initiations and rituals; poetic inspiration; and the madness of lovers.

For much of recorded history, deviant behavior has been considered supernatural and a reflection of the battle between good and evil.

When confronted with unexplainable, irrational behavior and by suffering and upheaval, people have perceived evil. C., all physical and mental disorders were considered the work of the devil.

Mental disorders were treated mainly under Traditional Chinese Medicine using herbs, acupuncture or "emotional therapy".

The Inner Canon of the Yellow Emperor described symptoms, mechanisms and therapies for mental illness, emphasizing connections between bodily organs and emotions.

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