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She was forced to put all working commitments on hold while undertaking treatment for the disease.
In an exclusive interview with The Australian Women's Weekly, Goodrem revealed that, since 2002, she had suffered from a head-to-toe rash, fatigue, weight loss, night sweats, and a lump on her neck.
As Delta was too unwell to perform at the ceremony herself, singer Darren Hayes performed a rendition of "Lost Without You" as a tribute, bringing an overwhelmed Goodrem to tears.
Her first full-length DVD Delta became the highest-selling music DVD by an Australian artist in Australia ever, with a certification of 11x platinum.
Reflecting on that period of her life, Goodrem said "It's weird to see pictures of that time. In March 2005, Goodrem starred in her first film role in Hating Alison Ashley, a film based on the children's novel by Robin Klein, with Goodrem acting the title character.Goodrem has a total of nine number-one singles and 17 top-ten hits on the ARIA Singles Chart.She has sold over eight million albums globally and overall has won three World Music Awards, 9 ARIA Music Awards, an MTV Video Music Award and several other awards.Delta Lea Goodrem (born 9 November 1984) is an Australian singer, songwriter, and actress.Goodrem signed to Sony Music at the age of 15 and released her debut album, Innocent Eyes (2003), which topped the ARIA Albums Chart for 29 consecutive weeks.